CY - Here's the math. I'd take the water route. Bring your wife. Hire a USCG captain. You'll have fun, learn LOTS and save the money and hassle of taking the flybridge off (and they never go back together exactly the same). But it's not cheaper than trucking it. It's more expensive, and worth it.
I looked up my schedule from the last half of our trip from St Lawrence Seaway to Chicago and also our trip up the Missouri River last year. Detroit to Harborside Marina (IL River mile 272) took 10 days incl. 3 weather days in port (I had my wife along and the boat can take more than the crew can). Harborside Marina to Alton, IL on the Mississippi took 5 days.
This is a 53MY. Cruise speed about 14 knots plus 30 min at 17 knots per day, except crossing Lake Michigan where we did 16.5-17.5 knots on plane for 7 hours straight. Running hours are real engine turning hours including harbors, going to fuel docks, no wakes, etc.
Day1 Day in Port (weather)
Day 2 Detroit via Lake Huron to Harrisville, MI Run Hrs=10 nm=150 nm/hr=15.0
Day 3 Harrisville to Macinac City Run Hrs = 11 nm=132 nm/hr=12.0
Day 4 Day in Port (weather)
Day 5 To Sleeping Bear Dunes Nat'l Park (Leland) Run Hrs=7 nm=91 nm/hr=13.0
Day 6 Leland, MI to Ludington, MI Run Hrs=8 nm=98 nm/hr=12.0
Day 7 Stay (weather)
Day 8 Cross Lake Michigan to Northpoint Marina IL Run Hrs=11 nm=125 nm/hr=14.0
Day 9 Northpoint to Burnham Harbor, Chicago Run Hrs=4 nm=50 nm/hr=12.5
Day 10 Chicago to Harborside Marina (IL mile 272) Run Hrs=11 nm=70 nm/hr=6.4
Day 11 Harborside Marina to Buffalo Rock Run Hrs=6 nm=40 nm/hr=6.7
Day 12 Arrive Peoria Run Hrs=7 nm=70 nm/hr=10.0
Day 13 Anchor out Run Hrs=8 nm=60 nm/hr=7.5
Day 14 Anchor out Run Hrs=7 nm=60 nm/hr=8.6
Day 15 Arrive Alton Marina Run Hrs=6 nm=60 nm/hr=10.0
Day 16-25 Mississippi River to Baton Rouge Run Hrs=95 nm=950 nm/hr=10.0
If you keep her at Baton Rouge, that's mile 230 of the Lower Mississippi and Alton is mile 203 of the Upper Mississippi. So.....
Alton to the Ohio River confluence is 203 nm, which is mile 980 of the Lower Mississippi.
Then mile 980 to Baton Rouge at mile 230 is an additional 750 nm.
Therefore, it's 950 nm on the Mississippi after you spend 10 days to get to Alton, IL. At a fast average of 95 nm per day including time for the locks, that's 10 days on the Mississippi at least. I don't know if you can really do 95 nm/day on the lower Mississippi. You gotta be careful of your wake on all river systems and slow to idle in "No Wake Zones".
If ya' got 25 days to go 2,086 nm, even if you break it up into 4 week long segments, it'd be great fun.
If your boat burns 1.5 gal/nm then it's 3,100 gals. of diesel at $2.50 = $7,800 in fuel.
18 or so transient slips @ 1.50 to $2 per foot is another $1,300.
Food at $30/day is $750.
USCG Captain @ $150/day to Harborside Marina is $1,650 if you can get your wife as first mate for rest of the trip home.
I guess it's about $12,000 for the whole trip.
1,200 miles by truck @ $5/mi is $6000.
Doug Shuman