I know a lot of folks don't like 5200 much but it's the only thing I use for that application (or any through-hull application). It is not difficult to remove a screw from 5200 - it just unscrews. I used it on all 200+ screws in the flybridge and all the various screws/fittings that hold things to the flybridge deck - davit bolts, dingy rack bolts, antennas, etc. I have removed many of them to change/relocate hardware and there is no problem unscrewing from 5200 IF you use an electric driver. By hand…well, that DOES get pretty tiresome.
I will readily admit that Hatt used 5200 in places on our 53 that although it worked perfectly for 30+ years, it is a real BEAR to remove…like around hoses going between bulkheads

I don't use it for that when replacing hoses.